Investigate
Disseminate
Advocate
The Science-Backed Path to Freedom from Unhealthy Drinking.
For thirty years, one of the most effective treatments for Alcohol Use Disorder has remained hidden in plain sight. The Naltrexone Alliance exists to change that.

About
Why Patients Choose Naltrexone
The Naltrexone Alliance promotes awareness of naltrexone as a safe, effective, and underused tool for helping people to have healthier relationships with alcohol. We work to expand access and implementation through the following initiatives:
Reduces Alcohol Noise
Helps break the urge-to-drink cycle.
Blunts Alcohol’s Reward
Makes drinking feel less reinforcing.
Fits Your Life
Daily, monthly, or targeted use — built for real routines.
Talk to your healthcare provider to learn whether naltrexone is right for you.
Our Work
Driving Change for an Underused, Evidence-Based Treatment
Naltrexone supports different recovery goals — from total abstinence to reducing heavy drinking gradually. You and your doctor decide which approach fits your journey.
For Clinicians —
Evidence-Aligned Practice
Up-to-date guidance, dosing insights, and practical tools to improve naltrexone implementation.
For Researchers —
Advancing the Science
Supporting studies, promoting data transparency, and expanding understanding of naltrexone’s long-term outcomes.
For the Public —
Empowering Recovery
Clear, accessible information to help patients and families make informed, stigma-free decisions.
Safety
A Note on Opioid Use
Naltrexone is an opioid antagonist.
If you take opioid pain medications or have Opioid Use Disorder, you must be opioid-free for a period before starting naltrexone — otherwise it may trigger sudden withdrawal.
This site focuses specifically on unhealthy drinking and Alcohol Use Disorder (AUD).

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